LIVE EVENT Q&A: Dr. Andrew Huberman Question & Answer in Los Angeles, CA

Huberman Lab· · Episode aired November 9, 2022· 10 min read
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High-Level Overview

This episode is the audience question-and-answer half of Andrew Huberman's live event at The Wiltern in Los Angeles, part of his lecture series The Brain Body Contract. Working without a guest, Huberman fields questions that range from ADHD and focus to cold water, trauma therapy, the gut microbiome, discipline, chasing dreams, psilocybin and why a sauna kills appetite. Several answers build on themes from the lecture that preceded it, especially dopamine as the single system behind motivation and the idea of working from delight instead of from grit alone.

The mood is relaxed and funny. He trades remarks with the audience, tells stories about his late bulldog Costello, a high school girlfriend's horse and Richard Feynman, and apologizes for a chilly theater. He is careful to say when he is not a clinician and when he is speculating. The session moves between practical tools, explanations of mechanism, and more reflective answers about how to live.

Table of contents

The Discussion Explores:

  • Non-medication approaches to ADHD and focus, including visual focus drills, short meditation and space-time bridging
  • What a 15-year-old should cultivate, and why self-awareness comes before tools
  • How long to stay in cold water, and the long dopamine rise that follows
  • Building confidence by managing stress and reframing failures as wins
  • How EMDR and simple walking quiet the brain's threat detection
  • Modulation versus mediation as a way to think about gut health, sleep and other fundamentals, plus palmar cooling
  • Lessons from skateboarding and from Feynman
  • Motivation, finding your direction, psilocybin research and the sauna

Deep Dive into Main Ideas

ADHD, Focus Training and Space-Time Bridging

Asked what happens in ADHD and whether it can be addressed without medication, Huberman first notes that he is not a clinician. People with ADHD, he says, can focus intensely on things they enjoy; a child who cannot attend in class becomes a laser with a favorite video game. His explanation is that the threshold for engaging the dopamine system is higher. He will not tell anyone to stop a prescription, and says drugs such as Vyvanse, Adderall and Ritalin clearly work, while some people choose milder options such as L-tyrosine, a dopamine precursor he says should be approached thoughtfully. His order of operations is behavioral tools first, with sleep and nutrition as prerequisites, and only then supplements or prescriptions.

The behavioral tools include visual focus exercises used in schools in China: one to three minutes of holding your gaze on a target, blinking as needed, because mental focus follows visual focus. He reminds the audience that "focusing always involves refocusing", and cites Wendy Suzuki's lab at NYU showing that a 13-minute daily breath-focused meditation significantly improves focus, though few people do it consistently.

An audience member prompts him to explain space-time bridging, which he calls a perceptual exercise more than a meditation. You begin with eyes closed, attending to the spot behind the forehead, where there are no sensory neurons and so nothing to feel, only thought. Then you open your eyes and, while staying aware of your breathing, focus at about hand distance, then farther, then farther again, finally imagining yourself as a small point in a vast setting before stepping back in. Because we slice time finely when focused up close and more broadly when looking far away, shifting spatial focus shifts time perception, which is why panoramic vision is calming. Under stress, people get stuck at one station; people who struggle with focus skip between them. He says data on the technique are still being collected.

Advice for a Fifteen-Year-Old

A 15-year-old who surfs, plays soccer and attends high school asks for five things to feel physically at their best. Huberman says they are already doing a lot right and starts with plenty of sleep. But instead of prescribing a meditation or deep-rest routine, he suggests something more basic: develop a keen awareness of what stresses you, what relaxes you and what delights you. He had a meditation practice as a youth because he was, in his words, a little haywire, and wishes he had also learned how he navigated stress and what he actually enjoyed. Those signals are your antennae, he says, and the teenage brain is in a fortunate period of heightened plasticity.

Cold Water, Adrenaline and Dopamine

Should you wait for the urge to get out of cold water to rise and then fall before leaving? Yes, he says, provided it is safe. The wall of resistance varies by day and time, and he broadens the point: when you strongly do not want to do something you know you should, you are already in the first wave of adrenaline, even if it feels like fatigue. Staying through the moment of wanting out teaches you where your mind goes. His rule is "Don't get out when you panic, unless it's dangerous." Leave once you have accomplished something.

The discomfort also predicts the reward. He cites a paper in the European Journal of Physiology reporting a 100 to 200% increase in dopamine lasting many hours after cold exposure. "It is not a subtle effect." Because the rise is slow, he says it does not crash the system, and he points to his colleague Anna Lembke's book Dopamine Nation, which describes patients using cold water to help themselves through the depressive phases of addiction recovery. He personally takes a warm shower afterward.

Confidence, Stress and Reframing Wins

On feeling more confident when intimidated, Huberman borrows a friend's image: in any endeavor you are back on your heels, flat-footed or leaning forward. Getting off your heels starts with calming yourself, because fear and stress shrink the options and creativity available. Normally the prefrontal cortex leads the regions that monitor internal state, such as the insula; under enough stress, as work by his colleague David Spiegel shows, that relationship reverses. He compares it to players running the game while the coach is dragged along. So the practical advice is real-time stress control, raising your stress threshold over time, and registering your wins.

He adds that the dopamine system depends heavily on interpretation. If you can truthfully frame a failure as a kind of win, you get the chemical benefit. He points to Nelson Mandela and Viktor Frankl, who found meaning in what they could control while imprisoned. "Dopamine is life force." There is one reward and motivation system, he says, not fifty.

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EMDR, Walking and Trauma

Huberman describes EMDR, in which a person moves their eyes from side to side while recounting a trauma, as one of four approved behavioral treatments for trauma, most effective for single events or repeated similar events and less so for an entire difficult childhood. Side-to-side eye movements have been shown to strongly quiet the amygdala, the threat-detection center. The same movements occur naturally when we walk forward without fixing on a target, which he says is part of why a walk without a phone is calming.

EMDR pairs that calmer state with the recounting of something normally triggering, a form of behavioral desensitization. Some researchers think it may involve a kind of hypnosis. Some people get great relief and others do not, and long-term brain imaging studies are few. He expects future treatment to combine therapies, including drugs that boost plasticity alongside methods like EMDR.

Modulation Versus Mediation, Gut Health and Palmar Cooling

Asked what excites him in health and wellness, Huberman says the field needs to pay attention to common themes across tools and to the difference between things that mediate an effect and things that modulate it. A fire alarm would modulate the audience's attention without being the mechanism of attention. A physiological sigh directly mediates calming, whereas good sleep modulates stress by making you less easily triggered.

The gut microbiome belongs in the modulating category, a little below sleep in importance. He notes that every mucosal surface has a microbiome and that the mouth heals without scarring. Fiber can help, he says, but low-sugar fermented foods such as natto, kimchi, sauerkraut, kombucha and certain yogurts do the most for gut health. Fixing the gut will not cure depression, but if it is off, improving it can lift mood, because gut bacteria produce chemicals that are converted to serotonin or dopamine in the brain. Sunlight, sleep, a healthy gut, exercise, good nutrition and social connection together create the background of health, and most people, he says, do not yet have those basics right. He hopes "modulating versus mediating" becomes a more common distinction, since it would end many pointless arguments.

Prompted by the audience, he explains palmar cooling, based on the work of Stanford's Craig Heller. The palms, soles of the feet and upper face have blood vessels arranged so that cooling them cools the body's core quickly. Doing so between sets or during endurance work can dramatically extend how long you can continue, by his account even doubling it, and he uses it for cognitive work as well. A device exists, but holding a container of cold water works, as long as it is not so cold that it constricts the vessels. He thinks the pandemic taught people that "there's no magic fairy coming to do it for you" where health is concerned.

Skateboarding, Feynman and Temperament

Skateboarding taught him about failure and gave him a community with high standards. He quotes a friend's line that "skateboarders hate everything", meaning how you do something matters as much as what you do. "I think it helped me develop a sense of taste." It also taught him to surround himself with people he enjoys, and he says running a lab and a podcast feels the same.

His favorite Feynman stories are, he says, mostly not fit for the stage, but he recounts the safe-cracking at Los Alamos and the bongo drums, and the lesson from Feynman's father on bird-watching: do not cloud your mind with names, look for the principles behind how different birds behave.

A horse owner reports that their easily stressed horse often does a double inhale and long exhale. Huberman says the sighing pattern certainly crosses species, and uses the question to describe autonomic temperament. Some animals, like his bulldog Costello, tilt toward calm; others, like whippets, toward arousal; humans also vary from birth. He chose Costello as a puppy because he ate from his littermates' bowls and then fell asleep, the opposite of Huberman's own temperament, and the dog helped regulate him.

Motivation and Finding Your Direction

On staying motivated, Huberman distinguishes two fuels. Grit, anger and competitiveness work but deplete you and demand long recovery. The more renewable fuel is delight, which draws on both dopamine and serotonin: finding a way to be loving, as a verb, toward what you are doing. In college he would tell himself he was going to fall in love with a subject he disliked by hunting for the gems in it. Getting sleep and stress under control is itself a form of discipline.

For achieving dreams, he draws on Robert Greene's idea of an early seed: something that delighted you in childhood. For him it was tropical fish in a Palo Alto pet shop, though what attracted him was really the organizing and predicting. The skill is noticing that pull, which he feels physically as a fidget in his left arm, and treating it as a compass. "You want to grow your antennae." You will not find it sitting on a mountain; you have to engage with the world, take measured risks and correct course. He cites Nobel laureate Carolyn Bertozzi, who as a student found excuses to stay in and read organic chemistry. "Reflection is good, but you need to get into action."

Psilocybin and the Sauna

On psilocybin he opens with cautions: "First of all, not for everybody." That applies especially to people with psychosis or addiction issues, and it remains illegal in most places. Citing Matthew Johnson, he says the data for microdosing are not really there, while trials of a single large guided dose for depression, and to some extent PTSD, eating disorders and end-of-life distress, are encouraging, with current data suggesting about two-thirds of participants get lasting relief. Citing Nolan Williams, he says psilocybin ranks near the bottom of perceived individual and societal risk among drugs, with alcohol quite high. A therapeutic guide matters because the altered state can attach to anything, such as music. Successful sessions seem to involve a moment of letting go, riding a wave of arousal from top to bottom.

On the sauna question he says, "I can only speculate." Uncomfortable heat releases dynorphin, which he describes as an appetite suppressant and which later increases the effect of the body's own opioids. He adds that four 20-minute sessions with five-minute breaks, once a week, produce very large growth hormone increases, with smaller increases when done more often.


Conclusion

Across a dozen unrelated questions, Huberman keeps returning to a few ideas. Get the modulating basics right: sleep, light, movement, food, a healthy gut and people you like. Learn to control stress in real time so the thinking brain stays in charge. Use discomfort such as cold deliberately, and stay with it past the first urge to quit. And pay attention to what delights you, because that signal sustains motivation better than grinding and points toward the work worth doing. He closes by thanking the audience and reminding them that he did not invent any of this; it is, in his telling, the biology everyone already carries.


This is a summary of "LIVE EVENT Q&A: Dr. Andrew Huberman Question & Answer in Los Angeles, CA" from Huberman Lab, giving you the GIST so you can decide if you want the REST. Listen to the full episode.

Mentioned in this episode

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  • Dopamine Nation · Anna Lembke(our summary)
    Huberman calls it amazing; describes patients helped by deliberate cold exposure.
  • Surely You're Joking, Mr. Feynman! · Richard Feynman(our summary)
    One of the Feynman books Huberman read and calls wonderful.
  • What Do You Care What Other People Think? · Richard Feynman(our summary)
    Named alongside the other Feynman book as wonderful.
  • CoolMitt
    Palm-cooling device he uses for cognitive work; says cold water works too.
  • L-tyrosine
    Dopamine precursor some use for focus; he urges caution and behavior first.
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